Scientific Program
Program as of June 2, 2024
Download program (PDF 741 kb)
Thursday June 6, 2024
08:00 – 10:00
Registration
10:00 – 10:10
Welcome and Opening Remarks
10:15 – 12:55
Session I
10:15 – 10:45
Juan Bonifacino (NIH, Bethesda, USA): Lysosome repair defects in hereditary spastic paraplegia
10:45 – 11:00
Selected abstract talk
Thomas Jacqmin (University Namur, Belgium): Insight into the disease mechanism of spastic paraplegia 21, a neurological disorder caused by the loss of maspardin, a cytosolic protein recruited on lysosomes
11:00 – 11:15
Selected abstract talk
Yanwei Su (FMP Berlin, Germany): The centronuclear myopathy protein and phosphoinositide phosphatase MTMR14 regulates lysosomal repair
11:15 – 11:30
Selected abstract talk
Jacques Neefjes (Leiden University Medical Centre, NL): Systems mapping of bi-directional endolysosomal transport through the crowded cell
11:30 – 11:55
Morning Break – Tea and Coffee
11:55 – 12:25
Gia Voeltz (University of Colorado – Boulder, USA): ER contact sites regulate endosome biogenesis and trafficking
12:25 – 12:55
Christian Hübner (University Hospital Jena, Germany): De-Stressing the ER by ER-Phagy
13:00 – 14:00
Lunch
14:00 – 15:30
Poster session I
15:30 – 17:00
Session II
15:30 – 16:00
Costas Demetriades (Max Planck Institute for Biology of Ageing, Cologne, Germany): Subcellular separation of nutrient signaling to mTORC1
16:00 – 16:15
Selected abstract talk
Chun Hei Li (Utrecht University, The Netherlands): Spatiotemporal proteomics reveals biosynthetic lysosomal membrane protein interactome in neurons
16:15 – 16:30
Selected abstract talk
Andrea Zanotti (DKFZ Heidelberg, Germany): Mechanistic characterization of different subcellular V-ATPase complexes
16:30 – 17:00
Gennaro Napolitano (TIGEM, Pozzuoli/Naples, Italy): Selective modulation of mTORC1 signaling at lysosomes
17:15 – 18:45
Snack buffet
18:45 – 20:00
Evening Session
18:45 – 19:15
Dejian Ren (University of Pennsylvania, Philadelphia, USA): Lysosomal ion channels in neurodegenerative diseases
19:15 – 19:30
Selected abstract talk
Marko Roblek (Medical University of Vienna, Austria): Orphan lysosomal solute carrier MFSD1 facilitates highly selective dipeptide transport
19:30 – 20:00
Sergio Grinstein (University of Toronto, Canada): Snx10 regulates lysosomal phosphoinositides and chloride transport
20:00 – 21:30
Poster Session II with reception
Friday June 7, 2024
09:15 – 10:30
Session III
09:15 – 09:45
Meng Wang (Baylor College of Medicine, Houston, USA): Lysosomal insights into organismal longevity
09:45 – 10:00
Selected abstract talk
Pathma Muthukottiappan (University of Bonn): Alterations in lipid homeostasis affect Ragulator-mediated lysosomal positioning
10:00 – 10:30
Monther Abu-Remaileh (Stanford University, USA): Intra-lysosomal lipid metabolism and neurodegeneration: from tool development to novel biology
10:30 – 12:00
Poster Session III
12:00 – 13:00
Lunch
13:00 – 14:30
Session IV
13:00 – 13:30
Kathrin Thedieck (University of Innsbruck, Austria): The mTOR-AHR pathway enhances lysosome function and translation under tryptophan stress
13:30 – 13:45
Selected abstract talk
Joao Mello-Vieira (Goethe Universität Frankfurt/Main, Germany): Metabolic control of lysosome functions during bacterial infection
13:45 – 14:15
Jan Carette (Stanford University, USA): Hold on for dear life: how viruses latch on to essential receptors to escape endosomes
14:15 – 15:45
Poster Session IV
15:45 – 16:45
Session V
15:45 – 16:15
Rushika Perera (University of California, San Francisco, USA): Decoding lysosomal mechanisms of cellular adaptation
16:15 – 16:45
Ivan Dikic (Goethe Universität Frankfurt am Main, Germany): Tumor immune evasion through IRGQ-directed autophagy and
lysosomal degradation of HLA class I proteins
16:45
Awards, Closing Remarks and End of Conference
