FOR2625 Symposium 2024

Program

Scientific Program

Program as of June 2, 2024
Download program (PDF 741 kb)


Thursday June 6, 2024                                             

08:00 – 10:00

Registration

10:00 – 10:10

Welcome and Opening Remarks

10:15 – 12:55

Session I        

10:15 – 10:45
Juan Bonifacino (NIH, Bethesda, USA): Lysosome repair defects in hereditary spastic paraplegia

10:45 – 11:00
Selected abstract talk
Thomas Jacqmin (University Namur, Belgium): Insight into the disease mechanism of spastic paraplegia 21, a neurological disorder caused by the loss of maspardin, a cytosolic protein recruited on lysosomes

11:00 – 11:15
Selected abstract talk
Yanwei Su (FMP Berlin, Germany): The centronuclear myopathy protein and phosphoinositide phosphatase MTMR14 regulates lysosomal repair

11:15 – 11:30
Selected abstract talk
Jacques Neefjes (Leiden University Medical Centre, NL): Systems mapping of bi-directional endolysosomal transport through the crowded cell

11:30 – 11:55
Morning Break – Tea and Coffee

11:55 – 12:25
Gia Voeltz (University of Colorado – Boulder, USA): ER contact sites regulate endosome biogenesis and trafficking

12:25 – 12:55
Christian Hübner (University Hospital Jena, Germany): De-Stressing the ER by ER-Phagy

13:00 – 14:00

Lunch

14:00 – 15:30

Poster session I

15:30 – 17:00

Session II        

15:30 – 16:00
Costas Demetriades (Max Planck Institute for Biology of Ageing, Cologne, Germany): Subcellular separation of nutrient signaling to mTORC1

16:00 – 16:15
Selected abstract talk
Chun Hei Li (Utrecht University, The Netherlands): Spatiotemporal proteomics reveals biosynthetic lysosomal membrane protein interactome in neurons

16:15 – 16:30
Selected abstract talk
Andrea Zanotti (DKFZ Heidelberg, Germany): Mechanistic characterization of different subcellular V-ATPase complexes

16:30 – 17:00
Gennaro Napolitano (TIGEM, Pozzuoli/Naples, Italy): Selective modulation of mTORC1 signaling at lysosomes

 

17:15 – 18:45

Snack buffet

18:45 – 20:00

Evening Session       

18:45 – 19:15
Dejian Ren (University of Pennsylvania, Philadelphia, USA): Lysosomal ion channels in neurodegenerative diseases

19:15 – 19:30
Selected abstract talk
Marko Roblek (Medical University of Vienna, Austria): Orphan lysosomal solute carrier MFSD1 facilitates highly selective dipeptide transport

19:30 – 20:00
Sergio Grinstein (University of Toronto, Canada): Snx10 regulates lysosomal phosphoinositides and chloride transport

20:00 – 21:30

Poster Session II with reception   


Friday June 7, 2024  

09:15 – 10:30

Session III        

09:15 – 09:45
Meng Wang (Baylor College of Medicine, Houston, USA): Lysosomal insights into organismal longevity

09:45 – 10:00
Selected abstract talk
Pathma Muthukottiappan (University of Bonn): Alterations in lipid homeostasis affect Ragulator-mediated lysosomal positioning

10:00 – 10:30
Monther Abu-Remaileh (Stanford University, USA): Intra-lysosomal lipid metabolism and neurodegeneration: from tool development to novel biology

10:30 – 12:00

Poster Session III

12:00 – 13:00

Lunch

13:00 – 14:30

Session IV        

13:00 – 13:30
Kathrin Thedieck (University of Innsbruck, Austria): The mTOR-AHR pathway enhances lysosome function and translation under tryptophan stress

13:30 – 13:45
Selected abstract talk
Joao Mello-Vieira (Goethe Universität Frankfurt/Main, Germany): Metabolic control of lysosome functions during bacterial infection

13:45 – 14:15
Jan Carette (Stanford University, USA): Hold on for dear life: how viruses latch on to essential receptors to escape endosomes

14:15 – 15:45

Poster Session IV

15:45 – 16:45

Session V    

15:45 – 16:15
Rushika Perera (University of California, San Francisco, USA): Decoding lysosomal mechanisms of cellular adaptation

16:15 – 16:45
Ivan Dikic (Goethe Universität Frankfurt am Main, Germany):
Tumor immune evasion through IRGQ-directed autophagy and
lysosomal degradation of HLA class I proteins

16:45

Awards, Closing Remarks and End of Conference